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Found 3 Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50191546'
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191546(2-[4-(biphenyl-2-ylmethoxy)-2-chlorophenyl]-1-cycl...)
Affinity DataIC50:  350nMAssay Description:Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191546(2-[4-(biphenyl-2-ylmethoxy)-2-chlorophenyl]-1-cycl...)
Affinity DataIC50:  2.85E+6nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191546(2-[4-(biphenyl-2-ylmethoxy)-2-chlorophenyl]-1-cycl...)
Affinity DataIC50:  2.86E+6nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article