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Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK3' and Ligand = 'BDBM15234'
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataKi:  3.00E+3nMAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant Plk3 (unknown origin) assessed as casein substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of AX7503 binding to recombinant Plk3 (unknown origin) expressed in HeLa cells by Western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of Plk3 in human A549 cells assessed as casein substrate phosphorylation by western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed