Found 6 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK4' and Ligand = 'BDBM2579'
Affinity DataKi: 2.60nMAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human PLK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PLK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.770nMAssay Description:Binding constant for PLK4 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.75nMAssay Description:Average Binding Constant for STK18; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 0.770nMAssay Description:Binding constant for PLK4 kinase domainMore data for this Ligand-Target Pair