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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50312606'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50312606(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-...)
Affinity DataKi:  29nMAssay Description:Inhibition of human recombinant mTOR assessed as reduction in GFP-4EBP1 phosphorylation after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50312606(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-...)
Affinity DataKi:  29nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50312606(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant mTOR by FRETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed