Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50439517'
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant mTOR (1360-2549) expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 after 30 mins by L...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR in PTEN deficient human PC3 cells assessed as inhibition of Akt phosphorylation at Ser473More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mTOR in PTEN deficient human PC3 cells assessed as inhibition of p70S6K phosphorylationMore data for this Ligand-Target Pair