Found 10 Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50170660' TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 1.03nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataKi: 1.03nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataKi: 2.38nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:In vitro binding affinity at Sigma opioid receptors on guinea pig brain membranes by [3H]3-PPP displacement.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:In vitro binding affinity at Sigma opioid receptor type 2 on guinea pig brain membranes by [3H]DTG displacement in the presence of [3H]pentazocine.More data for this Ligand-Target Pair
Affinity DataEC50: 1.07E+4nMAssay Description:Antiproliferative activity mediated by sigma 1 receptor in rat C6 glioma cells by MTT assayMore data for this Ligand-Target Pair
