Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50352935'
TargetSmoothened homolog(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50352935(CHEMBL1824916)
Affinity DataIC50:  7.20nMAssay Description:Antagonist activity at human SMO expressed in HEPM cells assessed as reduction of GLI expression after 24 hrs by Quantigene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50352935(CHEMBL1824916)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at mouse SMO expressed in NIH/3T3 cells transfected with Gli-dependent luciferase-reporter after 15 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed