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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50345911'
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345911(CHEMBL1783852 | CHEMBL1789669 | N-(diaminomethylen...)
Affinity DataIC50:  1.82nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345911(CHEMBL1783852 | CHEMBL1789669 | N-(diaminomethylen...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed