Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM161264' TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataIC50: 24nMAssay Description:1) Pre-spotted compounds (in neat DMSO) into compound plates. Vehicle control (neat DMSO), the positive control (20 mM DMSO stock tetracaine, 125 ...More data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataIC50: 24nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
