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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM154045'
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM154045(US9012443, 38)
Affinity DataIC50:  490nMAssay Description:293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM154045(US9012443, 38)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed