Found 5 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50077464'
Affinity DataIC50: 13nMAssay Description:Inhibition of human NaV1.7 assessed as reduction in peak inward current at -10 mV by manual whole cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of NaV1.7 in C57BL/6 mouse DRG neurons at -140 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human NaV1.7 by patchXpress 700A electrophysiology methodMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human NaV1.7 at -140 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inward peak current by ion-works quattro patch clamp electrophysiology methodMore data for this Ligand-Target Pair