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Found 2 Enz. Inhib. hit(s) with Target = 'Son of sevenless homolog 1 [564-1049]' and Ligand = 'BDBM609397'
TargetSon of sevenless homolog 1 [564-1049]()
Mirati Therapeutics

US Patent
LigandPNGBDBM609397(US11702418, Example 1-40)
Affinity DataKi:  0.270nMAssay Description:Table 22: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1 [564-1049]()
Mirati Therapeutics

US Patent
LigandPNGBDBM609397(US11702418, Example 1-40)
Affinity DataIC50:  171nMAssay Description:Table 24: This Example illustrates that exemplary compounds of the present invention prevent KRas-mediated GTP nucleotide exchange mediated by SOS1 t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent