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Found 3 Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM50156282'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Macaca fascicularis)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50156282(CHEMBL3780847)
Affinity DataIC50:  2nMAssay Description:Inhibition of CYP17A1 in cynomolgus monkey using [3H]-pregnenolone as substrate incubated for 45 mins by scintillation proximity assay in presence of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Macaca fascicularis)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50156282(CHEMBL3780847)
Affinity DataIC50:  3nMAssay Description:Inhibition of CYP17A1 in cynomolgus monkey adrenal microsomes using [3H]-pregnenolone as substrate incubated for 45 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50156282(CHEMBL3780847)
Affinity DataIC50:  21nMAssay Description:Inhibition of CYP17A1 in human adrenal microsomes using [3H]-pregnenolone as substrate incubated for 90 mins by scintillation proximity assay in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed