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Found 3 Enz. Inhib. hit(s) with Target = 'Thioredoxin reductase 1, cytoplasmic' and Ligand = 'BDBM50333880'
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)
Affinity DataKi:  1.90E+3nMAssay Description:Mixed-type inhibition of rat liver cytosolic TrxR1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)
Affinity DataKi:  8.10E+3nMAssay Description:Mixed-type inhibition of rat liver cytosolic TrxR1 at protein-substrate complex by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)
Affinity DataIC50:  4.41E+3nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed