Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM7962'
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of thromboxane synthase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against human thromboxane synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  28nMAssay Description:Compound was evaluated in vitro for the inhibition of Thromboxane synthase using [14C]-arachidonic acid as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against human microsomal thromboxane synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  106nMAssay Description:Inhibition of thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  106nMAssay Description:Inhibition of platelet microsomal thromboxane A2 synthetase in rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  150nMAssay Description:Tested for inhibition of thromboxane synthetase from spontaneously hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity of the compound to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  620nMAssay Description:Inhibition of platelet microsomal thromboxane A synthetase in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Thromboxane A2 synthase activity was assayed by measuring the fragmentation of prostaglandin H2 to form 12-hydroxy-5, 8,10-heptadecatrienoic acid and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of thromboxane B2 production in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.29E+3nMAssay Description:Tested for inhibitory activity against intact human platelet TXA2 formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of Thromboxane B2 formation in collagen-stimulated human platelets in platelet rich plasma.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of thromboxane formation at a concentration of 10e -6 M.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for inhibitory activity against thromboxane synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for the inhibition of thromboxane formation (thromboxane synthetase) in platelets at a concentration of 10e-4 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Thromboxane A2 synthase after oral administration of 0.03 mmol/kgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed