Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Thyrotropin-releasing hormone receptor' and Ligand = 'BDBM50196451'
TargetThyrotropin-releasing hormone receptor(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50196451((2S)-1-{(2S)-3-(1-methyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]N(1)-Me-His-TRH from TRHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50196451((2S)-1-{(2S)-3-(1-methyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]N(1)-Me-His-TRH from TRHR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50196451((2S)-1-{(2S)-3-(1-methyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50196451((2S)-1-{(2S)-3-(1-methyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed