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Found 2 Enz. Inhib. hit(s) with Target = 'Trace amine-associated receptor 1' and Ligand = 'BDBM122294'
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM122294(US8729113, 1)
Affinity DataKi:  1.70nM ΔG°:  -46.5kJ/moleT: 2°CAssay Description:Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM122294(US8729113, 1)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed