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Found 6 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily A member 1' and Ligand = 'BDBM50327667'
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327667(CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at -30 mV holding potential by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327667(CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at 75 mV holding potential by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327667(CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...)
Affinity DataEC50:  0.0603nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327667(CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as time point of maximal current amplitude by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327667(CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...)
Affinity DataEC50:  83.2nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at -30 mV holding potential by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327667(CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at -75 mV holding potential by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed