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Found 5 Enz. Inhib. hit(s) with Target = 'Transporter' and Ligand = 'BDBM50006774'
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.80nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]-Nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.80nMAssay Description:Ability to displace [3H]- nisoxetin from Norepinephrine transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to norepinephrine (NE) transporter in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter (NET) in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataIC50:  35nMAssay Description:Inhibition of [3H]mazindol binding to Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed