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Found 2 Enz. Inhib. hit(s) with Target = 'Trifunctional purine biosynthetic protein adenosine-3' and Ligand = 'BDBM50272231'
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50272231((S)-2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of GARFTase in human KB cells assessed as inhibition of [14C]glycine incorporation into [14C]formylGAR in presence of azaserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50272231((S)-2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed