Found 2 Enz. Inhib. hit(s) with Target = 'Trifunctional purine biosynthetic protein adenosine-3' and Ligand = 'BDBM50272273'
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of GARFTase in human KB cells assessed as inhibition of [14C]glycine incorporation into [14C]formylGAR in presence of azaserineMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair