Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase
assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based
on t...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Inhibition of human BTK assessed as decrease in anti-mouse IgD antibody stimulated BCR mediated CD69 upregulation in whole blood preincubated for 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 364nMAssay Description:Inhibition of mouse BTK assessed as decrease in anti-mouse IgD antibody stimulated BCR mediated CD69 upregulation in whole blood preincubated for 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mouse BTK assessed as decrease in anti-CD3epsilon antibody stimulated TCR mediated CD69 upregulation in whole blood preincubated for 1 ...More data for this Ligand-Target Pair