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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50580181'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50580181(CHEMBL5083068)
Affinity DataIC50:  25nMAssay Description:Inhibition of Btk (unknown origin) assessed as inhibition of phosphorylation of FAM-labelled peptide substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50580181(CHEMBL5083068)
Affinity DataEC50:  398nMAssay Description:Inhibition of human Btk in human Raji cells assessed as PhosY223 measured after 30 mins by cellular HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed