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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM475700'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM475700((4aR,8aS)-8a-ethyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataEC50:  2nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM475700((4aR,8aS)-8a-ethyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataEC50:  1nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent