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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50434787'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50434787(CHEMBL2386635 | US10487083, Example C | US10703751...)
Affinity DataIC50:  0.600nMAssay Description:11-point dosing series were made for each compound by serially diluting 1:3 or 1:4 in DMSO, with point 12 being a DMSO control. From the serial dilut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50434787(CHEMBL2386635 | US10487083, Example C | US10703751...)
Affinity DataEC50:  3.34nMAssay Description:Human baculovirus-expressed Janus kinase (JAK) 1, 2, 3 and tyrosin kinase (TYK) 2 were purchased from Carna Biosciences, Inc (#08-144, -045, -046, -1...More data for this Ligand-Target Pair
In DepthDetails US Patent