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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM185700'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
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US Patent
Ligand
BDBM185700
(US10875847, Compound Oclacitinib | US9161939, 1a |...)
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Affinity Data
IC50: 95.1nM
pH: 7.4
Assay Description:
Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk...
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