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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM527818'
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM527818((2R,4R)-4-amino-8- (8-((2,3- dichlorophenyl)thio) ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of SHP-2 activity by small molecule inhibitors was monitored by a biochemical DiFMUP pseudosubstrate-fluorogenic assay. SHP-2 enzyme at fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent