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Found 3 Enz. Inhib. hit(s) with Target = 'Urease subunit alpha' and Ligand = 'BDBM50099857'
TargetUrease subunit alpha(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50099857(ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...)
Affinity DataIC50:  2.92E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit alpha(Helicobacter pylori ATCC43504)
Wuhan Textile University

LigandPNGBDBM50099857(ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...)
Affinity DataIC50:  4.25E+4nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
TargetUrease subunit alpha(Helicobacter pylori)
Minia University

LigandPNGBDBM50099857(ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...)
Affinity DataIC50:  1.20E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair