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Found 4 Enz. Inhib. hit(s) with Target = 'Vascular cell adhesion protein 1' and Ligand = 'BDBM50098512'
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50:  3.50E+4nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced VCAM-1 expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50:  4.00E+4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed