Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM50117486'
TargetVasopressin V2 receptor(Homo sapiens (Human))
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]-AVP from human V2 receptor expressed in human HeLa cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)
Affinity DataIC50:  230nMAssay Description:Binding affinity against Vasopressin V2 receptor was determined in Brattleboro ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)
Affinity DataIC50:  330nMAssay Description:Binding affinity of the compound against human Vasopressin V2 receptor expressed in HeLa cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)
Affinity DataEC50:  189nMAssay Description:Agonist activity at human V2 receptor expressed in human HeLa cells assessed as stimulation of cAMP accumulation by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed