Found 3 Enz. Inhib. hit(s) with Target = 'Voltage-dependent N-type calcium channel subunit alpha-1B' and Ligand = 'BDBM50465797' TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
