Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM135821'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135821(US10085990, Example 118 | US10568888, Example 118 ...)
Affinity DataIC50:  206nMAssay Description:A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135821(US10085990, Example 118 | US10568888, Example 118 ...)
Affinity DataIC50:  206nMAssay Description:The assay buffer was prepared by diluting 5× supplied Tween-based buffer in 1:5 in water to make 1× buffer. Add desired additive to buffer (DTT or Mn...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135821(US10085990, Example 118 | US10568888, Example 118 ...)
Affinity DataIC50:  206nMAssay Description:A TR-FRET-based phosphodiesterase assay kit from Molecular Devices was used to test whether these compounds were indeed direct inhibitors of the PDE4...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135821(US10085990, Example 118 | US10568888, Example 118 ...)
Affinity DataIC50:  206nMT: 2°CAssay Description:The assay buffer was prepared by diluting 5× supplied Tween-based buffer in 1:5 in water to make 1× buffer. Add desired additive to buffer (DTT or Mn...More data for this Ligand-Target Pair
In DepthDetails US Patent