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Found 2 Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM408558'
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408558(US10358435, Example 74 | US10358435, Example 75)
Affinity DataKi:  0.420nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408558(US10358435, Example 74 | US10358435, Example 75)
Affinity DataKi:  8.90nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent