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Found 2 Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM480487'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM480487(US10626113, Compound D | US10899756, Compound D)
Affinity DataIC50:  0.0700nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM480487(US10626113, Compound D | US10899756, Compound D)
Affinity DataIC50:  0.0700nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent