Found 6 Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50241831' TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 0.0440nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 0.0440nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 0.0560nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 0.0560nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP or FAM-cAMP as substrate incubated for 60 mins and measured by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 0.0560nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 0.0560nMAssay Description:Inhibition of human recombinant PDE5A1 using FAM-labelled cGMP as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
