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Found 6 Enz. Inhib. hit(s) with Target = 'fMet-Leu-Phe receptor' and Ligand = 'BDBM50559829'
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human FPR1 expressed in CHO cells assessed as reduction cAMP accumulation incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Mus musculus)TBA
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at mouse FPR1 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human FPR1 overexpressing CHO cells assessed as reduction in intracellular cAMP level incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human FPR1 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetfMet-Leu-Phe receptor(Mus musculus)TBA
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  500nMAssay Description:Agonist activity at mouse FPR1 expressed in CHO cells assessed as reduction cAMP accumulation incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed