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Found 37 of ic50 for UniProtKB: P11541
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM235735(US9359371, 3)
Affinity DataIC50:  8.89nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM235755(US9359371, 38)
Affinity DataIC50:  58nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM235742(US9359371, 11)
Affinity DataIC50:  61nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  140nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304788(CHEMBL594160 | methyl 4-(3-chloro-4-methoxybenzyla...)
Affinity DataIC50:  140nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50272569(CHEMBL4128481)
Affinity DataIC50: >142nMAssay Description:Inhibition of bovine retina PDE6A using 3',5'-[3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM235762(US9359371, 46)
Affinity DataIC50:  310nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304789(CHEMBL604271 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  320nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304792(CHEMBL595104 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  340nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50246252(CHEMBL521075 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  460nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357870(CHEMBL1916130)
Affinity DataIC50: >500nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304787(CHEMBL596489 | ethyl 4-(3-chloro-4-methoxybenzylam...)
Affinity DataIC50:  600nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM235765(US9359371, 50)
Affinity DataIC50:  660nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304786(CHEMBL603422 | methyl 4-(3-chloro-4-methoxybenzyla...)
Affinity DataIC50:  710nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357872(CHEMBL1916132)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357871(CHEMBL1916131)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357826(CHEMBL1915892)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357825(CHEMBL1915891)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50319165(2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304791(CHEMBL592986 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM235764(US9359371, 48)
Affinity DataIC50:  1.11E+3nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357828(CHEMBL1915912)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357832(CHEMBL1916091)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357816(CHEMBL1915906)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357806(CHEMBL1915896)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357865(CHEMBL1916125)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: >3.00E+3nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357822(CHEMBL1915888)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357864(CHEMBL1916124)
Affinity DataIC50:  3.44E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357863(CHEMBL1916123)
Affinity DataIC50:  3.57E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357849(CHEMBL1916108)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357803(CHEMBL1916113)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50304785(2-(4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-6-[...)
Affinity DataIC50:  7.95E+3nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357847(CHEMBL1916106)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357820(CHEMBL1915910)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma

US Patent
LigandPNGBDBM50357854(CHEMBL1916114)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibition of recombinant bovine PDE6A using [3H]cGMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed