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Found 149 of ic50 for UniProtKB: P08581
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517021((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- hydroxypr...)
Affinity DataIC50:  3.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517049((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  4.30nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517011((S)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...)
Affinity DataIC50:  5.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517014((R)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...)
Affinity DataIC50:  6nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517051((R)-5-bromo-N-(3- fluoro-4-((3-((1- hydroxypropan-...)
Affinity DataIC50:  6nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517044((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  7.20nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517002((R)—N-(3-fluoro-4-((3-((1-hydroxypropan-2-yl)amino...)
Affinity DataIC50:  8.40nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517082((S)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- methoxypr...)
Affinity DataIC50:  9nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516997((R)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...)
Affinity DataIC50:  9.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517030((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  9.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517045((R)-1-ethyl-N-(3-fluoro- 4-((3-((1- hydroxypropan-...)
Affinity DataIC50:  10nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517080((S)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...)
Affinity DataIC50:  10.8nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517033((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  11.6nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517109((R)-1-(cyclopropylmethyl)-N-(3-fluoro-4-((3-((1-me...)
Affinity DataIC50:  17.8nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517009(N-(3-fluoro-4-((3- (((2R,3R)-3- hydroxybutan-2- yl...)
Affinity DataIC50:  18.1nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517010((R)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...)
Affinity DataIC50:  19.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517036((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  20.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517084((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  21.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517078((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...)
Affinity DataIC50:  22nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517091((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- methoxypr...)
Affinity DataIC50:  22.4nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517037((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  25.6nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517081((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  26.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517003((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)(me...)
Affinity DataIC50:  27.1nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517099((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  27.4nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517035((R)-6-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  28.3nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517046((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  29.2nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517028((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  29.6nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517006((S)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...)
Affinity DataIC50:  29.7nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516981(N-(4-((3-((4,4-difluoro-1- hydroxybutan-2- yl)amin...)
Affinity DataIC50:  31nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517047((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  31nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517076((R)—N-(3-fluoro-4-((3-((1-methoxypropan-2-yl)amino...)
Affinity DataIC50:  31.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517038((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  33nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516998((S)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...)
Affinity DataIC50:  33.4nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516985((R)-N-(3-fluoro-4-((3-((1- hydroxybutan-2- yl)amin...)
Affinity DataIC50:  34.4nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517094(N-(4-((3-((4,4- difluorobutan-2- yl)amino)-1H- pyr...)
Affinity DataIC50:  35.2nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517007(N-(3-fluoro-4-((3-((2- hydroxy-2- methylpropyl)ami...)
Affinity DataIC50:  36nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517034((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  36.2nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517090((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  38.7nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517005((R)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...)
Affinity DataIC50:  40.7nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517050((R)-1-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...)
Affinity DataIC50:  41.8nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517102((S)-N-(4-((3-((1- ethoxypropan-2- yl)amino)-1H- py...)
Affinity DataIC50:  42.9nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517092((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  43.3nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517126(N-(4-((3-amino-1H-pyrazolo[3,4-b]pyridin-4-yl)oxy)...)
Affinity DataIC50:  44.4nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516967(N-(3-fluoro-4-((3- (((1s,3s)-3- (hydroxymethyl)cyc...)
Affinity DataIC50:  44.6nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516979(N-(3-fluoro-4-((3-((1- hydroxy-4-methoxybutan- 2-y...)
Affinity DataIC50:  45nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517022((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...)
Affinity DataIC50:  45.8nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517024((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  46nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517047((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  46.7nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517040((R)-1-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  50.4nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [L1195V](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517093((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  50.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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