Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of kd for UniProtKB: P28335
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241702(CHEMBL463207 | [N-methyl-3H]LSD)
Affinity DataKd:  52.8nMAssay Description:Binding affinity to human 5HT2C receptor expressed in HEK293 cells by saturation binding methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224303(CHEMBL283686)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224302(CHEMBL31783)
Affinity DataKd:  43nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224305(CHEMBL285355)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50590657(EPLIVANSERIN | Eplivanserin | SR-46349 | SR46349)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to 5-HT2 receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKd:  1.58E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor in piglet choroid plexus using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50056445(1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...)
Affinity DataKd:  5.01E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor in piglet choroid plexus using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM85099(CAS_141474-54-6 | SDZ SER 082 FUMARATE | SDZ SER-0...)
Affinity DataKd:  16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in calf caudate membranes using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM85099(CAS_141474-54-6 | SDZ SER 082 FUMARATE | SDZ SER-0...)
Affinity DataKd:  200nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in calf caudate membranes using [3H]5-HT; Not determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed