Compile Data Set for Download or QSAR
maximum 50k data
Found 310 of ic50 for UniProtKB: P23458
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103727(US10112907, Example 00033 | US10206907, Compound 2...)
Affinity DataIC50:  50nMAssay Description:JAK1 (IC50): Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) is purchased from Carna Biosciences. 10 ng of JAK1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348894(N-(5-(biphenyl-4-yl)- [1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348897(N-(5-(4-benzoylphenyl)- [1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348899(N-(5-(4-(benzyloxy)phenyl)- [1,2,4]triazolo[1,5-a]...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348900(N-(5-(4-(N- cyclopropylsulfamoyl)phenyl)- [1,2,4]t...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348902(N-(5-(4-(benzyloxy)-3- fluorophenyl)- [1,2,4]triaz...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348903(N-(5-(4-(piperidine-1- carbonyl(phenyl)- [1,2,4]tr...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348905(N-(5-(4-(pyrrolidine-1- carbonyl)phenyl)- [1,2,4]t...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348907(N-(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazol...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348909(N-(5-(4-(2- phenylacetamido)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348911(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348915(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348916(4-(2- (cyclopropanecarboxamido)- [1,2.4]triazolo[1...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348917(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348919(N-(5-(4-(4- fluorophenylsulfonamido) phenyl)-[1,2,...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348922(N-(5-(4-(pyridin-3- ylmethoxy)phenyl)- [1,2,4]tria...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348923(N-(5-(4-(pyridin-2- ylmethoxy)phenyl)- [1,2,4]tria...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348925(N-(5-(4- (cyclobutylmethoxy)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348926(N-(5-(4- (cyclopentyloxy)phenyl)- [1,2,4]triazolo[...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348927(N-(5-(4- (cyclohexylmethoxy)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348932(N-(5-(4-phenoxyphenyl)- [1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348934(N-(5-(4-((1-methyl-1H- pyrazol-3-yl)methylmethyl- ...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348935(N-(5-(4-((3,5- dimethylisoxazol-4- yl)methoxy)phen...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348936(N-(5-(4-((1,3-dimethyl-1H- pyrazol-5-yl)methyldime...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348937(N-(5-(4-(2-(3,5-dimethyl-1H- pyrazol-4-yl)ethyldim...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348938(N-(5-(4-((5-methylisoxazol-3- yl)methoxy)phenyl)- ...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348940(N-(5-(4-(2- fluorophenylsulfonamido) phenyl)-[1,2,...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348942(N-benzyl-4-(2- (cyclopropanecarboxamido)- [1,2,4]t...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348943(Cyclopropanecarboxylic Acid [5-(6-benzyloxy-pyridi...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348944(N-(5-(4-(1,2,3,4- tetrahydroisoquinoline-2- carbon...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50031742(CHEMBL3360348 | US10206907, Compound 59)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348946(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348948(N-(5-(4-((1,5-dimethyl-1H- pyrazol-3-yl)methyldime...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348950(N-(5-(4-(pyridine-3- sulfonamido)phenyl)- [1,2,4]t...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348952(N-(5-(4-(pyridin-3-yl)phenyl)- [1,2,4]triazolo[1,5...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348957(N-(5-(4-(4-methylpiperazine- 1-carbonyl)phenyl)- [...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348958(N-(5-(4- (benzylamino)phenyl)- [1,2,4]triazolo[1,5...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348960(N-(5-(4-(4-benzoylpiperidine- 1-carbonyl)phenyl)- ...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348961(N-(5-(4-(4-benzyl-1,4- diazepane-1-carbonyl)phenyl...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348962(N-(5-(4-(2- phenylethylsulfonamido) phenyl)-[1,2,4...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348963(N-(5-(4- (phenylmethylsulfonamido) phenyl)-[1,2,4]...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348964(N-(5-(4-((6- (trifluoromethyl)pyridin-3- yl)methox...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348965(N-(5-(4- (phenylsulfonamido)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348968(N-(5-(4-(4- propylphenylsulfonamido) phenyl)-[1,2,...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348969(N-(5-(4-(4-(4- chlorophenyl)piperidine-1- carbonyl...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348970(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348971(N-(5-(4-(2-(3- fluorophenyl)ethylsulfonamido) phen...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348972(N-(5-(2-fluoro-4-(piperidine- 1-carbonyl)phenyl)- ...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348973(N-butyl-4-(2- (cyclopropanecarboxamido)- [1,2,4]tr...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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