BindingDB PrimarySearch

Found 124 of ic50 for UniProtKB: P26431

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

IC50: 0.0680nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353110(CHEMBL1829122)

IC50: 0.0730nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353113(CHEMBL1829125)

IC50: 0.0840nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353114(CHEMBL1829126)

IC50: 0.0910nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353111(CHEMBL1829123)

IC50: 0.110nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353097(CHEMBL1829132)

IC50: 0.310nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353116(CHEMBL1829128)

IC50: 0.530nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353098(CHEMBL1829133)

IC50: 0.560nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353103(CHEMBL1829139)

IC50: 0.670nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353102(CHEMBL1829138)

IC50: 0.920nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50378116(CHEMBL1202327)

IC50: 0.940nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353105(CHEMBL1829117)

IC50: 1.06nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353099(CHEMBL1829134)

IC50: 1.10nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297583(CHEMBL560806 | N''-[2-(1H-benzimidazol-2-ylthio)-5...)

IC50: 1.17nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50207580(CHEMBL234074 | N-[3-(5-nitro-1H-benzoimidazol-2-yl...)

IC50: 1.42nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50353101(CHEMBL1829137)

IC50: 1.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297577(CHEMBL549392 | N''-[2-(1H-benzimidazol-2-ylthio)-2...)

IC50: 1.73nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297571(CHEMBL561343 | N''-{2-[(5-nitro-1H-benzimidazol-2-...)

IC50: 1.74nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345911(CHEMBL1783852 | CHEMBL1789669 | N-(diaminomethylen...)

IC50: 1.82nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297563(CHEMBL550813 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)

IC50: 1.90nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297578(2-{[(1E)-2-(1,3-benzothiazol-2-ylsulfanyl)-4,5,6-t...)

IC50: 1.98nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297580(CHEMBL560884 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)

IC50: 2.34nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297562(CHEMBL563178 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)

IC50: 2.44nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345911(CHEMBL1783852 | CHEMBL1789669 | N-(diaminomethylen...)

IC50: 3.60nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50207583(CHEMBL234279 | N-[2-(5-nitro-1H-benzoimidazol-2-yl...)

IC50: 4.05nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345917(CHEMBL1783857 | N-(diaminomethylene)-3-(N-methylsu...)

IC50: 4.48nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297575(2-{[(1E)-2-(1H-1,3-benzodiazol-2-ylsulfanyl)-4,5,6...)

IC50: 10.8nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50207572(CHEMBL234072 | N-[4-(5-nitro-1H-benzoimidazol-2-yl...)

IC50: 11nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345908(CHEMBL1783849 | N-(diaminomethylene)-2-((4-(2,3,4-...)

IC50: 11.1nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297576(CHEMBL561142 | N''-[2-(1H-benzimidazol-2-ylthio)-5...)

IC50: 11.2nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345914(CHEMBL1783830 | N-(diaminomethylene)-3-sulfamoyl-4...)

IC50: 11.5nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297569(CHEMBL563763 | N''-{5-chloro-2-[(5-nitro-1H-benzim...)

IC50: 12.2nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115243((S)-N-[7-(5-fluoro-2-methylphenyl)-4-methyl-(7S)-5...)

IC50: 14nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345912(CHEMBL1783853 | N-(diaminomethylene)-4-nitro-3-((4...)

IC50: 14.2nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345916(CHEMBL1783856 | N-(diaminomethylene)-3-(N-methylsu...)

IC50: 15nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297566(CHEMBL549925 | N''-{2-[(5-methoxy-1H-benzimidazol-...)

IC50: 16.8nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115239((S)-N-[7-(2,5-dichloro-3-thienyl)-4-methyl-(7S)-5,...)

IC50: 17nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50345913(CHEMBL1783854 | N-(diaminomethylene)-3-nitro-4-(1-...)

IC50: 18.7nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115246(CHEMBL543867 | N-[7-(2-chloro-5-fluorophenyl)-4-me...)

IC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115248(CHEMBL552723 | N-[7-(3-chloro-2-thienyl)-4-methyl-...)

IC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115271(CHEMBL556009 | N-[7-(2,5-dichloro-3-thienyl)-4-met...)

IC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115267(CHEMBL102546 | N-[7-(2-chlorophenyl)-4-methyl-(7S)...)

IC50: 20nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297579(CHEMBL550335 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)

IC50: 20.3nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297574(CHEMBL557259 | N''-[2-(1H-benzimidazol-2-ylthio)-5...)

IC50: 21.4nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115268(CHEMBL554001 | N-[7-(2-chloro-3-thienyl)-4-methyl-...)

IC50: 22nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50297564(CHEMBL550611 | N''-{6-fluoro-2-[(5-methoxy-1H-benz...)

IC50: 25.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115238(CHEMBL552865 | N-[7-(2-chlorophenyl)-4-methyl-5,6,...)

IC50: 26nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50207574(CHEMBL233048 | N-{3-(morpholine-4-sulfonyl)-4-[4-(...)

IC50: 27.1nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50207579(CHEMBL232838 | N-{3-methanesulfonyl-4-[4-(5-nitro-...)

IC50: 27.8nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Sodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL

BDBM50115245(CHEMBL554215 | N-[4-methyl-7-(3-thienyl)-5,6,7,8-t...)

IC50: 30nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

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