Compile Data Set for Download or QSAR
maximum 50k data
Found 158 of ic50 for UniProtKB: P56192
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50112575(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration against Methionyl-tRNA synthetase in a pyrophosphate exchange assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50222901(CHEMBL1163059)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against Escherichia coli Methionyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50112577(2-[3-(6-Ethyl-8-iodo-1,2,3,4-tetrahydro-quinolin-4...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory concentration against Staphylococcus aureus Methionyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143330((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143333((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143329((S)-1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-y...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143334((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)
Affinity DataIC50:  87nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129541(3-[5-(2',4'-Dichloro-biphenyl-4-yl)-3-tetrazol-1-y...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129527(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129528(2-[5-(2',4'-Dichloro-biphenyl-4-yl)-3-tetrazol-1-y...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143331((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143337((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143332((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129534(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129551(CHEMBL74224 | {[5-(2',4'-Dichloro-biphenyl-4-yl)-1...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143343((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143341((S)-1-{[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50112576(2-(3-(3,4-dichlorobenzylamino)propylamino)quinolin...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory concentration against Methionyl-tRNA synthetase in a pyrophosphate exchange assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129553(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-4-ylmet...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143342((S)-1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yliden...)
Affinity DataIC50:  510nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129539(1-[5-(2',4'-Dichloro-biphenyl-4-yl)-1-(2-methoxy-p...)
Affinity DataIC50:  530nMAssay Description:Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129546(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...)
Affinity DataIC50:  630nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129533(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-ylmet...)
Affinity DataIC50:  660nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143328((S)-1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-y...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143329((S)-1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-y...)
Affinity DataIC50:  730nMAssay Description:Inhibition of Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143339((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)
Affinity DataIC50:  760nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143338((S)-1-{[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-ylide...)
Affinity DataIC50:  810nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143340((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129550(5-(2',4'-Dichloro-biphenyl-4-yl)-2-pyridin-4-ylmet...)
Affinity DataIC50:  910nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129532(5-(2',4'-Dichloro-biphenyl-4-yl)-1-ethyl-1H-pyrazo...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129543(5-(2',4'-Dichloro-biphenyl-4-yl)-2-pyridin-3-ylmet...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143336((S)-1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yliden...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366861(CHEMBL605595)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against Escherichia coli Methionyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129526(1-(3-Carboxy-phenyl)-5-(2',4'-dichloro-biphenyl-4-...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366868(CHEMBL605589)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against Escherichia coli Methionyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143332((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129548(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-ylmet...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143342((S)-1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yliden...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129544(5-(2',4'-Dichloro-biphenyl-4-yl)-1-(2-methoxy-phen...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143335((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129528(2-[5-(2',4'-Dichloro-biphenyl-4-yl)-3-tetrazol-1-y...)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366863(CHEMBL605806)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against Escherichia coli Methionyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129546(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129542(5-(2',4'-Dichloro-biphenyl-4-yl)-2-pyridin-2-ylmet...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129529(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393794(CHEMBL2159537)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143339((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)
Affinity DataIC50:  3.11E+3nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129535(5-(2',4'-Dichloro-biphenyl-4-yl)-1H-pyrazole-3-car...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50129554(1-Carboxymethyl-5-(2',4'-dichloro-biphenyl-4-yl)-1...)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50143330((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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