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Found 12 of ic50 for UniProtKB: P14616
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human IRR using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human IRR using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IRR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50554817(CHEMBL4764610)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human INSRRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50347388(CHEMBL1234833)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of IRRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant IRR (943 to 1266 residues) using myelin basic protein as substrate after 40 mins by [gamma-33ATP] by radiometric scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IRR using MBP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IRRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IRRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged INSRR cytoplasmic domain expressed in baculovirus expression system using tyrosine-1 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of human InsRRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed