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Found 586 of ic50 for UniProtKB: P53985
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50:  8nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50:  11nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50608633(CHEMBL3582501)
Affinity DataIC50:  25nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50:  34nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50:  37nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50:  48nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345287(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropyl...)
Affinity DataIC50:  54.5nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356766(US10214492, Example 130)
Affinity DataIC50:  55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM546629(2-([1-[(2-Chlorophenyl)methyl]-5-(4- cyclopropoxyt...)
Affinity DataIC50:  55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345271(1-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345295(1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50:  100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356858(US10214492, Example 207 | US11292767, Example 207)
Affinity DataIC50:  102nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356738(US10214492, Example 108 | US11292767, Example 108)
Affinity DataIC50:  102nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356768(US10214492, Example 132 | US11292767, Example 132)
Affinity DataIC50:  104nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM22000(7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...)
Affinity DataIC50:  105nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055506(CHEMBL3326270)
Affinity DataIC50:  116nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356781(US10214492, Example 143 | US11292767, Example 143)
Affinity DataIC50:  152nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356904(US10214492, Example 255 | US11292767, Example 255)
Affinity DataIC50:  154nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356861(US10214492, Example 210 | US11292767, Example 210)
Affinity DataIC50:  154nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055505(CHEMBL3326265)
Affinity DataIC50:  192nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356782(US10214492, Example 144 | US11292767, Example 144)
Affinity DataIC50:  201nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345291(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclobutoxy...)
Affinity DataIC50:  204nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345298(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopentyl...)
Affinity DataIC50:  204nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356771(US10214492, Example 135 | US11292767, Example 135)
Affinity DataIC50:  220nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356771(US10214492, Example 135 | US11292767, Example 135)
Affinity DataIC50:  220nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356758(US10214492, Example 122 | US11292767, Example 122)
Affinity DataIC50:  251nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356890(US10214492, Example 241 | US11292767, Example 241)
Affinity DataIC50:  254nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345281(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50:  302nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345260(2-[[5-(4-Chlorophenyl)-1-[(2,4- dichlorophenyl)me...)
Affinity DataIC50:  303nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345334(US10202350, Example 81 | US10214492, Example 81 | ...)
Affinity DataIC50:  303nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345259(2-[[5-(4-Chlorophenyl)-1-[(2,4- dichlorophenyl)me...)
Affinity DataIC50:  400nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345264(2-[[5-(3-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  404nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345296(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclobutylm...)
Affinity DataIC50:  404nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356737(US10214492, Example 107 | US11292767, Example 107)
Affinity DataIC50:  454nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356911(US10214492, Example 262 | US11292767, Example 262)
Affinity DataIC50:  454nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345257(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  454nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055500(CHEMBL3326256)
Affinity DataIC50:  548nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356767(US10214492, Example 131 | US11292767, Example 131)
Affinity DataIC50:  650nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM356767(US10214492, Example 131 | US11292767, Example 131)
Affinity DataIC50:  650nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055503(CHEMBL3326259)
Affinity DataIC50:  669nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055502(CHEMBL3326252)
Affinity DataIC50:  858nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345271(1-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345295(1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50:  1.20E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345271(1-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345295(1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50:  1.20E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345259(2-[[5-(4-Chlorophenyl)-1-[(2,4- dichlorophenyl)me...)
Affinity DataIC50:  1.80E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM345259(2-[[5-(4-Chlorophenyl)-1-[(2,4- dichlorophenyl)me...)
Affinity DataIC50:  1.80E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055501(CHEMBL3326257)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM50055504(CHEMBL3326264)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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