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Report error Found 67 of affinity data for UniProtKB/TrEMBL: P51617
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26311(3-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)ph...)
Affinity DataIC50:  1.20E+3nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50097418(CHEMBL41816)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26317(N-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50:  2.50E+3nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26309(CHEMBL459888 | N-[4-(2-{thieno[3,2-d]pyrimidin-4-y...)
Affinity DataIC50:  3.20E+3nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26319(2-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50:  4.90E+3nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26321(1-methyl-1-phenyl-3-[5-(2-{thieno[3,2-d]pyrimidin-...)
Affinity DataIC50:  7.20E+3nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26318(N-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26310(4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-N-[3...)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26312(3-[3-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)ph...)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26316(3-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM357015(US10214511, Example 19 | US10676460, Example 19)
Affinity DataIC50:  3.98E+4nMAssay Description:The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM357015(US10214511, Example 19 | US10676460, Example 19)
Affinity DataIC50:  3.98E+4nMAssay Description:The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM357015(US10214511, Example 19 | US10676460, Example 19)
Affinity DataIC50:  3.98E+4nMAssay Description:The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50452728(CHEMBL4213175)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mouse Aurora kinase A by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50613394(CHEMBL5278465)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mouse Aurora kinase A by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50613392(CHEMBL5270581)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mouse Aurora kinase A by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetAurora kinase A(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mouse AURAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
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