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Found 159 of ic50 for UniProtKB: P61168
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054716(1H-Indazole-3-carboxylic acid [4-(4-benzo[d]isothi...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054711(4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054702(3-Amino-benzo[b]thiophene-2-carboxylic acid [4-(4-...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054715(4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  6nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002213(1-(4-Fluoro-phenyl)-2-{1-[2-(1H-indol-3-yl)-ethyl]...)
Affinity DataIC50:  7nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054712(3H-Benzoimidazole-4-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  7.60nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054705(2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054718(3-Amino-thiophene-2-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002288(1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phe...)
Affinity DataIC50:  10nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054713(2-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054708(1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054703(CHEMBL358268 | Quinoline-8-carboxylic acid [4-(4-b...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002242(2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1...)
Affinity DataIC50:  14nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054717(3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054707(CHEMBL344994 | Pyridine-2-carboxylic acid [4-(4-be...)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054714(3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]i...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054709(CHEMBL141494 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054710(1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054706(1H-Indole-7-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50:  28nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054704(2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benz...)
Affinity DataIC50:  34nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002283(2-(1-Benzyl-piperidin-3-yl)-1-(4-fluoro-phenyl)-et...)
Affinity DataIC50:  34nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002220(1-(4-Fluoro-phenyl)-2-(1-phenethyl-piperidin-4-yl)...)
Affinity DataIC50:  42nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054719(CHEMBL356498 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Affinity DataIC50:  47nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002234(1-(4-Fluoro-phenyl)-4-{4-[2-(4-fluoro-phenyl)-acet...)
Affinity DataIC50:  55nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002198(1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluoro-phenyl)-ethy...)
Affinity DataIC50:  57nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280817(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280829(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280815(CHEMBL56377 | N-{2-[4-(5-Fluoro-1H-indol-3-ylmethy...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280818(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280826(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280827(1'-{2-[4-(5-fluoro-1H-3-indolylmethyl)hexahydro-1-...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280824(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280820(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280828(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280822(4-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280832(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280823(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280821(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280819(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280816(CHEMBL293729 | N-{2-[4-(5-Fluoro-1H-indol-3-ylmeth...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280831(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280825(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50280830(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: >100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002260(1-Cyclopropylmethyl-4-(2,4-dichloro-phenoxymethyl)...)
Affinity DataIC50:  111nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002290(1-Benzyl-4-[2-(4-fluoro-phenoxy)-ethyl]-piperidine...)
Affinity DataIC50:  114nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002209(1-(2,2-Dichloro-1-methyl-cyclopropylmethyl)-4-(4-f...)
Affinity DataIC50:  179nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002297(2-(1-Cyclopropylmethyl-piperidin-3-yl)-1-(4-fluoro...)
Affinity DataIC50:  185nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002250(1-(4-Fluoro-phenyl)-2-[1-(4-trifluoromethyl-benzyl...)
Affinity DataIC50:  195nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50002301(4-(4-Fluoro-benzyloxymethyl)-1-naphthalen-1-ylmeth...)
Affinity DataIC50:  219nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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