Compile Data Set for Download or QSAR
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Found 31 Enz. Inhib. hit(s) with all data for entry = 50030710
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300382(4-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)py...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300401(2-(5-bromo-2-(2,3-dihydro-1H-inden-4-ylamino)pyrim...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300383(4-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)py...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300384(2-(5-chloro-2-(4-(3-(dimethylamino)-2,2-dimethylpr...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300385(2-(5-bromo-2-(3-(dimethylamino)-2-methylphenylamin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300386(2-(5-bromo-2-(2-methoxy-4-(2-methyl-1H-imidazol-1-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300387(1-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)py...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300388(2-(5-chloro-2-(4-(3-(ethylamino)pyrrolidin-1-yl)-2...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300389(2-(5-chloro-2-(4-(3-(dimethylamino)pyrrolidin-1-yl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300390(1-(4-(5-bromo-4-(2-(N-methylsulfamoyl)phenylamino)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300402(5-chloro-N2-(2-methoxy-4-morpholinophenyl)-N4-(2-(...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300391(2-(5-chloro-2-(2-methoxy-4-((1-methylpiperidin-3-y...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300392(CHEMBL574839 | N-(1-(4-(5-chloro-4-(2-(N-isopropyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300393(2-(5-bromo-2-(4,4'-dimethoxybiphenyl-3-ylamino)pyr...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300394((R)-1-(4-(5-chloro-4-(2-(methylcarbamoyl)phenylami...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300395(2-(5-bromo-2-(2,4-dimethoxyphenylamino)pyrimidin-4...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300396(2-(2-(1H-indazol-7-ylamino)-5-bromopyrimidin-4-yla...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300403(2-(5-bromo-2-(2,4-difluorophenylamino)pyrimidin-4-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300397(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-me...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300404(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300398(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-me...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50249287(2-(2-aminoethylamino)-4-(m-tolylamino)pyrimidine-5...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50249452(2-(2-aminoethylamino)-4-(p-tolylamino)pyrimidine-5...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300399(3-(5-((5-chloro-2-oxoindolin-3-ylidene)methyl)-4-m...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50249417(2-(2-aminoethylamino)-4-(3-cyanophenylamino)pyrimi...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300405(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50249478(2-(2-aminoethylamino)-4-(phenylamino)pyrimidine-5-...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM4887(3-(4-methyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM4811((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50300400(3,10,13,16,23-pentaazahexacyclo[14.7.0.0^{2,10}.0^...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed