Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50048386
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.513nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.589nMAssay Description:Inhibition of binding of [3H]pirenzepine to muscarinic receptor (M1) in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  4nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M2) in rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213289(CHEMBL165220)
Affinity DataKi:  5nMAssay Description:Inhibition of binding of [3H]pirenzepine to muscarinic receptor (M1) in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  6.5nMAssay Description:Inhibition of binding of [3H]pirenzepine to muscarinic receptor (M1) in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213288(Spirotramine)
Affinity DataKi:  13nMAssay Description:Inhibition of binding of [3H]pirenzepine to muscarinic receptor (M1) in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213289(CHEMBL165220)
Affinity DataKi:  14nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M2) in rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  14nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M2) in rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  26nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213289(CHEMBL165220)
Affinity DataKi:  32nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  35nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  37nMAssay Description:Inhibition of binding of [3H]pirenzepine to muscarinic receptor (M1) in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213287(CHEMBL163901)
Affinity DataKi:  40nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213287(CHEMBL163901)
Affinity DataKi:  76nMAssay Description:Inhibition of binding of [3H]pirenzepine to muscarinic receptor (M1) in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  174nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213287(CHEMBL163901)
Affinity DataKi:  182nMAssay Description:Antagonism of 5-HT2A receptor of rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213289(CHEMBL165220)
Affinity DataKi:  302nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213288(Spirotramine)
Affinity DataKi:  537nMAssay Description:Antagonism to the H1 receptor of guinea pig ileum was determinedMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213288(Spirotramine)
Affinity DataKi:  631nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M2) in rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  794nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M2) in rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213288(Spirotramine)
Affinity DataKi:  977nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50213287(CHEMBL163901)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In DepthDetails