Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50031686
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317227((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317229((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317230((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317231((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-((d...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317243((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(di...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317244((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317232((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(3-((d...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317235((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317236((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317228((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317234((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317239((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-mor...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317237((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317230((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317231((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-((d...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317240((E)-4-(2,4-dichlorophenylamino)-7-(4-morpholinobut...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317229((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317243((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(di...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317227((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317244((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317232((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(3-((d...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317238((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317235((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317234((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317228((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317237((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317241((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-(4-mor...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317236((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317239((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-mor...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317242((E)-4-(2,4-dichlorophenylamino)-6-(4-morpholinobut...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317240((E)-4-(2,4-dichlorophenylamino)-7-(4-morpholinobut...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317238((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TPL2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed