Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50014067
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137828(6-(5-Hydroxy-6-morpholin-4-ylmethyl-1,3-dioxo-1H,3...)
Affinity DataIC50:  500nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137838(6-(6-Bromo-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  1.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137829(6-(5-Hydroxy-1,3-dioxo-1H,3H-benzo[de]isoquinolin-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137843(8-Biphenyl-3-yl-8-oxo-octanoic acid (2-amino-pheny...)
Affinity DataIC50:  1.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137848(6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic a...)
Affinity DataIC50:  2.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137832(8-Naphthalen-2-yl-8-oxo-octanoic acid (2-amino-phe...)
Affinity DataIC50:  2.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137839(6-(5-Hydroxy-1,3-dioxo-6-piperidin-1-ylmethyl-1H,3...)
Affinity DataIC50:  2.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137826(8-Biphenyl-4-yl-8-oxo-octanoic acid (2-amino-pheny...)
Affinity DataIC50:  2.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137831(8-Oxo-8-(6-phenyl-pyridin-3-yl)-octanoic acid (2-a...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137845(6-(5-Methyl-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-h...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137849(6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137830(6-(5-Hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137847(6-(5-Hydroxy-1,3-dioxo-6-piperidin-1-ylmethyl-1,3-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137834(6-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)-hexan...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137833(6-(5-Hydroxy-6-morpholin-4-ylmethyl-1,3-dioxo-1,3-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137844(6-(1-Oxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid ...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137840(6-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137836(8-(3',4'-Dimethoxy-biphenyl-4-yl)-8-oxo-octanoic a...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137842(8-(4-Methoxy-phenyl)-8-oxo-octanoic acid (2-amino-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137850(6-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataIC50:  5.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137835(8-(4-Bromo-phenyl)-8-oxo-octanoic acid (2-amino-ph...)
Affinity DataIC50:  6.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137841(6-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-yl)-hexanoic ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137827(8-Oxo-8-phenyl-octanoic acid (2-amino-phenyl)-amid...)
Affinity DataIC50:  9.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137837(8-Oxo-8-(4-pyridin-3-yl-phenyl)-octanoic acid (2-a...)
Affinity DataIC50:  1.00E+4nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137846(6-(4-Oxo-4H-quinazolin-3-yl)-hexanoic acid (2-amin...)
Affinity DataIC50:  1.20E+4nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137848(6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic a...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137842(8-(4-Methoxy-phenyl)-8-oxo-octanoic acid (2-amino-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137844(6-(1-Oxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid ...)
Affinity DataEC50:  9.90E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137830(6-(5-Hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137836(8-(3',4'-Dimethoxy-biphenyl-4-yl)-8-oxo-octanoic a...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137845(6-(5-Methyl-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-h...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137846(6-(4-Oxo-4H-quinazolin-3-yl)-hexanoic acid (2-amin...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137841(6-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-yl)-hexanoic ...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137837(8-Oxo-8-(4-pyridin-3-yl-phenyl)-octanoic acid (2-a...)
Affinity DataEC50:  2.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137839(6-(5-Hydroxy-1,3-dioxo-6-piperidin-1-ylmethyl-1H,3...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137831(8-Oxo-8-(6-phenyl-pyridin-3-yl)-octanoic acid (2-a...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137827(8-Oxo-8-phenyl-octanoic acid (2-amino-phenyl)-amid...)
Affinity DataEC50:  2.50E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137850(6-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataEC50: >2.50E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137829(6-(5-Hydroxy-1,3-dioxo-1H,3H-benzo[de]isoquinolin-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137835(8-(4-Bromo-phenyl)-8-oxo-octanoic acid (2-amino-ph...)
Affinity DataEC50:  1.50E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137832(8-Naphthalen-2-yl-8-oxo-octanoic acid (2-amino-phe...)
Affinity DataEC50:  2.50E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137838(6-(6-Bromo-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137828(6-(5-Hydroxy-6-morpholin-4-ylmethyl-1,3-dioxo-1H,3...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137843(8-Biphenyl-3-yl-8-oxo-octanoic acid (2-amino-pheny...)
Affinity DataEC50:  2.50E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137826(8-Biphenyl-4-yl-8-oxo-octanoic acid (2-amino-pheny...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137834(6-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)-hexan...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137849(6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed